OUTCOME OF DOUBLE BLIND COMPARATIVE STUDY OF SULFASALAZINE AND HYDROXYCHLOROQUINE IN EARLY UNDIFFERENTIATED INFLAMMATORY ARTHRITIS

Objective:Undifferentiated inflammatory arthritis is one of the requirements for being diagnosed in patient doesnt meet classical criteria recognized arthritis. which no approved treatment algorithm exist. Sulfasalazine and hydroxychloroquine used this trial early Undifferentiated Methods: A six-month, double-blind, randomized experiment was conducted. 100 consecutive patients. ESR, morning stiffness, number swollen joints, a pain score are all measured on monthly basis. Patients with certain rheumatological diagnoses were excluded.. Results: The completed by 74 patients.The sulfasalazine group responds better more promptly. There have been respond terms grip strength, score, duration stiffness compared to hydroxychloroquine.The 26 withdrawal from research prematurely owing side effects, gastrointestinal symptoms primary cause actively treated group. Conclusions:Our statistics lead us conclusion that provides an earlier response than hydroxychloroquine. Response significant benefit patients quality life.